Choline acetyltransferase (abbreviated "ChAT") is an
enzyme that is synthesized within the body of a
neuron. It is then transferred to the
nerve terminal via
axoplasmic flow. The role of choline acetyltransferase is to join
Acetyl-CoA to
choline, resulting in the formation of the
neurotransmitter acetylcholine.
It is often used as a marker, immunohistochemically, for motor neurons (motoneurons).
See also
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