Choline_acetyltransferase

Choline acetyltransferase

Choline acetyltransferase (abbreviated "ChAT") is an enzyme that is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. The role of choline acetyltransferase is to join Acetyl-CoA to choline, resulting in the formation of the neurotransmitter acetylcholine.

It is often used as a marker, immunohistochemically, for motor neurons (motoneurons).

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