Chlorzoxazone is a centrally acting
muscle relaxant used to treat muscle
spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes. It is sold as
Parafon Forte, a combination of chlorzoxazone and
acetaminophen. Possible side effects include
dizziness,
lightheadedness,
malaise,
nausea,
vomiting, and liver dysfunction.
External links
- Dong DL, Luan Y, Feng TM, Fan CL, Yue P, Sun ZJ, Gu RM, Yang BF. (2006). "Chlorzoxazone inhibit contraction of rat thoracic aorta.". Eur J Pharmacol
- Park J, Kim K, Park P, Ha J (2006). "Effect of high-dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe.". J Clin Pharmacol 46 (1): 109–14.
- Wan J, Ernstgård L, Song B, Shoaf S (2006). "Chlorzoxazone metabolism is increased in fasted Sprague-Dawley rats.". J Pharm Pharmacol 58 (1): 51–61.