Chlorzoxazone

Chlorzoxazone

Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes. It is sold as Parafon Forte, a combination of chlorzoxazone and acetaminophen. Possible side effects include dizziness, lightheadedness, malaise, nausea, vomiting, and liver dysfunction.

External links

  • Dong DL, Luan Y, Feng TM, Fan CL, Yue P, Sun ZJ, Gu RM, Yang BF. (2006). "Chlorzoxazone inhibit contraction of rat thoracic aorta.". Eur J Pharmacol
  • Park J, Kim K, Park P, Ha J (2006). "Effect of high-dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe.". J Clin Pharmacol 46 (1): 109–14.
  • Wan J, Ernstgård L, Song B, Shoaf S (2006). "Chlorzoxazone metabolism is increased in fasted Sprague-Dawley rats.". J Pharm Pharmacol 58 (1): 51–61.

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