Printers was nagged by injuries during the 2005 season, and was embroiled in a quarterback controversy with Dickenson. Ultimately, the Lions bowed out in the playoffs with Dickenson taking the large majority of playing time. Having turned down a three year, $1 million contract extension from the Lions prior to the 2005 season, Printers turned down a three year, $1.2 million (CAD) offer from the Lions in January 2006, opting to sign a three year, $1.03 million (USD) deal with the Kansas City Chiefs of the National Football League. Printers struggled in spot duty for the Chiefs' in the 2006 NFL pre-season, and did not see any regular season playing time, spending most of the season on the practice roster.
After going undrafted in the 2002 NFL Draft, Printers joined the British Columbia Lions for the 2003 CFL season on a three year contract as their third-string quarterback, and saw little playing time, attempting only two passes. During the 2004 season, he unseated Spergon Wynn as backup quarterback and replaced starter Dave Dickenson when Dickenson went down with an injury. After completing 325 of 494 pass attempts for 5,088 yards and 35 touchdowns with 10 interceptions and rushing for 469 yards and 9 touchdowns, he was named the Most Outstanding Player of the 2004 season, becoming known as a dynamic quarterback able to improvise and make big plays both passing and rushing. He played a key role in the Lions' eight game winning streak, 13-5 record, and first place finish in the West Division standings. His 35 passing touchdowns and 10.3 yards-per-pass average led the league; he tied Edmonton's Jason Maas for a league-best 65.8 completion percentage, and his rushing stats were best among QBs.
In the West Division Final against the Saskatchewan Roughriders, Printers was forced to leave the game with a shoulder injury in the fourth quarter, with the score tied 14-14. Dickenson, having recovered from knee surgery and shared quarterbacking duties with Printers late in the season, played the rest of the game and threw a touchdown pass in the Lions' 27-24 overtime victory. Dickenson would start and play the entire Grey Cup game against the Toronto Argonauts, which the Lions lost by a score of 27-19.
Printers had surgery on his right hallux in the offseason, and turned down a three year, $1 million contract extension from the Lions. With Printers recovering, Dickenson won the starting job and led the team to an 11-0 start. Printers took over as starter after Dickenson was injured in the 13th game. After the 11-0 start, the Lions lost six of their last seven regular season games, including the regular season finale against the Roughriders, in which Dickenson returned and replaced Printers in the second half. Dickenson started and played all but the last three minutes of the West Division Final against the Edmonton Eskimos, which the Lions lost 28-23.
Throughout the 2005 season Printers was embroiled in a quarterback controversy with Dickenson over who should start as pivot and was nagged by shoulder and toe injuries. Ultimately, Printers saw relatively little playing time, completing 131 of 216 pass attempts for 1671 yards, 9 touchdowns and 6 interceptions, with 336 yards rushing and 2 rushing TDs. In January 2006, he turned down a three year, $1.2 million (CAD) offer from the Lions, opting to sign a three year, $1.03 million (USD) deal with the Kansas City Chiefs.
Printers was expected to compete with Chiefs 2006 draft pick Brodie Croyle for a backup quarterback position, but struggled in his preseason debut in the second quarter of an August 12, 2006 game against the Houston Texans at Reliant Stadium. In limited action in the Chiefs' four pre-season games, Printers completed 12 of 23 pass attempts for 109 yards with one interception and rushed 5 times for 20 yards. He was cut by the Kansas City Chiefs on September 2, 2006, prior to the start of the regular season. He was signed to the Chiefs' practice squad on September 4, 2006. On October 28, 2006, he was signed to the Chiefs' 53-man roster. After being demoted to the practice roster once again, he travelled to Vancouver and attended the November 12 BC Lions West Division Final playoff game against the Saskatchewan Roughriders at BC Place, but was barred from the sidelines by Lions head coach Wally Buono. The Lions won the game 45-18 with Dave Dickenson at quarterback. In late November 2006, the Toronto Argonauts expressed an interest in negotatiating a contract with him, although he was still under contract to the Chiefs and the BC Lions still owned his CFL rights. On December 31, 2006, Printers signed a three year deal with the Chiefs and was promoted to the active roster.
Printers was released by the Chiefs on September 1, 2007. His conversation with Chiefs Director of Player Personnel Ray Farmer was documented on episode 5 of HBO's Hard Knocks: Training Camp with the Kansas City Chiefs series. Printers said that his release was "unbelievable," especially since he had done everything asked of him during training camp. Printers was replaced by Quarterback Tyler Thigpen.
Printers signed with the Hamilton Tiger-Cats on September 6, 2007 for a reported $500,000 a season, making him the highest paid player in the CFL.
Printers holds the CFL record for single-game completion percentage, set with the BC Lions in a 49-11 victory over the Hamilton Tiger-Cats at Ivor Wynne Stadium on August 13, 2004. Printers completed 20 of 22 passes (90.9%) for 303 yards, including four touchdowns to slotback Geroy Simon. Simon's four TD catches also tied a team record. As the Lions' starting quarterback for most of the 2004 season, Printers was also instrumental in Geroy Simon's league-best 14 touchdown receptions and league-best 1750 receiving yards, which broke the Lions' club record for receiving yards in a season. The previous record was 1731 yards, set by Darren Flutie in 1994.