He is best remembered for mounting the original production of Bizet's Carmen in 1875. His friendship with Ernest Reyer led to him providing libretti for Sigurd and Salammbô. Du Locle was responsible for completing the libretto of Don Carlos after the death of Joseph Mery. He also played a key role in the genesis of Aida in 1869-70. In 1876 a financial dispute arose with Verdi, and Du Locle moved to Capri. According to Charles Pigot, Du Locle inspired the subject, words and music of Bizet's Djamileh. He was a pall-bearer at Bizet's funeral and made a speech at his interment at Père Lachaise.