Bromobenzene

Bromobenzene

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Bromobenzenes are a group of halobenzenes formed in a substitution reaction between bromine and benzene with a hydrogen bromide biproduct. The name strictly refers to monobromobenzene, a benzene with a single bromine; however it can be used to refer to a benzene containing any number of bromine molecules. Bromobenzene is a clear pale yellow liquid.

Uses

Bromobenzene can be used to prepare the corresponding Grignard reagent, phenylmagnesium bromide. This can be used in a number of fashions, e.g. the reaction with carbon dioxide to prepare benzoic acid. Bromobenzene is used in the production of drugs.

Pharmacology

It is a toxic substance and can cause liver and nervous system damage if inhaled, ingested or absorbed through the skin.

References

See also

See Chlorobenzene for extra detail as to the mechanism of the formation. Mechanism is by electrophillic substitution.

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