The village was home to a yeshiva, notable as a historic centre of Hasidism, created and led by the tsadik of Bobov. In 1900 the Jewish population of Bobowa numbered 749.
It was also the home of Bolesław Wieniawa-Długoszowski who became "President of Poland for a day" in 1939. During the Second World War it became a "concentration village" where the Jews from the surrounding area were imprisoned. The general's brother Kazek was the mayor and was able to save at least one Jew. Almost all were finally killed. This is described by one of the few survivors Professor Samuel P. Oliner of Humbolt State University, California. He describes these events in his autobiography, Restless Memories. He devoted his academic career to the study of Altruism, having himself been rescued by a Polish peasant woman called Balwina.
After the war Grand Rabbi Shlomo Halberstam (The Second) (1907 – August 2, 2000) re-established the Bobov (Hasidic dynasty) in America. He was the son of Rabbi Ben Zion Halberstam (1874-1941) of Bobov (Bobowa), who died in the Holocaust. Initially based in the neighbourhood of Borough Park in Brooklyn, New York, it now has branches in the Williamsburg section of Brooklyn; Monsey, New York; Miami; Montreal; Toronto; Antwerp; London and Israel.
Bobowa is also one of two (besides Koniaków) villages in Poland famous for traditional art of lace-making. Since 2000 it houses an annual Bobbin lace Festival.