The term is widely used by regional development agencies, international organizations, biotechnology companies. It is closely linked to the evolution of the biotechnology industry. The ability to study, understand and manipulate genetic material has been possible due to scientific breakthroughs and technological progress.
The evolution of the biotechnology industry and its application to agriculture, health, chemical or energy industries is a classic example of bioeconomic activity.
Enriquez and Martinez' 2002 Harvard Business School working paper, "Biotechonomy 1.0: A Rough Map of Biodata Flow", showed the global flow of genetic material into and out of the three largest public genetic databases: GenBank, EMBL and DDBJ. The authors then hypothesized about the economic impact that such data flows might have on patent creation, evolution of biotech startups and licensing fees. An adaptation of this paper was published in Wired magazine in 2003.