Biliverdin is a green
pigment formed as a byproduct of
heme breakdown. It consists of four linearly connected
pyrrole rings (a
tetrapyrrole). Biliverdin is formed when a
heme prosthetic group is cleaved at its α-
methine bridge. The resulting water-soluble biliverdin (C
33H
34N
4O
6) is then converted to
bilirubin (C
33H
36N
4O
6) by
biliverdin reductase in macrophages of the
reticuloendothelial system. The changing color of a
bruise from deep purple to yellow over time is a graphical indicator of this reaction.
Biliverdin is also present in the bile juice which is secreted by the liver and also imparts color to the bile juice.
The green-blooded skinks of the genus Prasinohaema possess such high (and would otherwise be toxic) levels of biliverdin in their blood that their tissues are colored a bright green.
External links
Tetrapyrroles