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Aspergillus nidulans
1 reference results for: Aspergillus nidulans
Wikipedia
Aspergillus nidulans (also called Emericella nidulans) is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology for over 50 years, being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, pathogenesis, and metabolism. It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner.

Genome

The genome of A. nidulans, sequenced at the Broad Institute, was published in December 2005. It is 30 million base pairs in size and is predicted to contain around 9,500 protein-coding genes on eight chromosomes.

Recently, several caspase-like proteases were isolated from A.nidulans samples under which programmed cell death had been induced. Findings such as these play a key role in determing the evolutionary conservation of the mitochondrion within the eukaryotic cell, and its role as an ancient proteobacterium capable of inducing cell death.

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Last updated on Monday July 07, 2008 at 11:55:41 PDT (GMT -0700)
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