The department covers an area of 63,612 km² (24,427 sq mi), and has an estimated population of 5,819,358 (2006 estimate). Antioquia borders with the Cordoba Department and the Caribbean Sea to the north, Chocó to the west, to the east it borders the departments of Bolivar, Santander and Boyaca, and to the south the departments of Caldas and Risaralda.
Antioquia is one of the most touristic departments in Colombia, and continues to increase the number of hotels and visitors from all over the world.
Medellín is Antioquia's capital city, and the second largest city in the country. Other important towns are Santa Fe de Antioquia, the old capital located on the Cauca, and Puerto Berrío on the Magdalena.
Antioquia was primarily populated by Caribs, although some scattered groups of Muiscas were present in the Darién region (in modern day Panama), a coastal region in the far north of Antioquia. However, there are no historical records for these groups of Muiscas in Antioquia.
The Caribs present in Antioquia were further classified into smaller groups, called families. Some of the most prominent indigenous families in the region include the Catías, Nutabes and Tahamíes, which all inhabited the central region of Antioquia.
An important group that inhabited southern Antioquia was the Quimbaya, whose presence is substantiated by historical records.
There were other groups, but the Quimbaya, Carib and Muisca tribes were the most prominent conglomerates that were found by the conquistadors upon their arrival in Antioquia. The Quimbayas had little to do with the evolution of the department, because Jorge Robledo, the main conquistador of Antioquia, quickly subjected the few Quimbaya that he found, and the rest disappeared quickly.
The history was centered then in the turbulent relationships of the Spaniards with the Caribs. Despite the number of Caribs and their well-known warring culture, they would end up dominated or exterminated by the Iberians in the process of conquest and colonization.
During these processes bloody confrontations were presented that caused the surviving natives to disperse, and even commit suicide, before they were subjected. Many of the survivors fled to the department of Chocó. Thus, in Antioquia, the natives disappeared almost completely. At present, the indigenous population of the department of Antioquia scarcely reaches 0.5% of the total population.
In 1541, Marshal Jorge Robledo left the now-gone Spanish establishment of Arma, a little below Aguadas in the south of Antioquia, for an expedition toward the north on the Cauca River.
Farther north, in 1541, Robledo would found Santa Fe de Antioquia. In 1813, Santa Fe de Antioquia was declared the capital of the County of Antioquia, and this lasted until 1826 when Medellin was made the capital.
to facilitate the Department's administration. These 9 regions contain a total of 126 municipalities. The 9 subregions with their municipalities are:| Southwestern Antioquia | Eastern Antioquia | Northeastern Antioquia |
|---|---|---|
| Northern Antioquia | Western Antioquia | Bajo Cauca Antioquia |
|---|---|---|
| Magdalena Medio Antioquia | Urabá Antioquia | Medellín Metropolitan Area |
|---|---|---|
The local inhabitants of Antioquia are known as antioqueños. Of the five main regional groups in Colombia, the predominant group in Antioquia are known as paisa, referring to those living in the Paisa region, which covers most of Antioquia, as well as the departments of Caldas, Risaralda and Quindío.
Despite 80% of the department's territory being mountainous, Antioquia also has a coast on the Caribbean Sea, in the lowland area of the Urabá. This area has a tropical climate and is of high strategical importance due to its location.