She holds a B.M. degree in voice from the Oberlin Conservatory of Music, a B.A. in linguistics from Oberlin College, and an M.F.A. in electronic music from Mills College, where she studied with Pauline Oliveros and David Rosenboom.
Her solo works combine her singing and speaking voice with electronic loops and samples triggered with electronic drums. Her multi-layered compositions incorporate musical styles including opera, rock, Medieval music, and world music. For ten years she led the experimental band Amy X Neuburg & Men.