Aerophagia is diagnosed in 8.8% of mentally retarded patients. where the coordination between swallowing and respiration is not well defined. In one case aerophagia was successfully treated with thorazine, an antipsychotic sometimes used to treat hiccups.
Aerophagia is a dangerous side effect of non-invasive ventilation (NIV), commonly used in treatments of respiratory problems and cardiovascular critical care or in surgery when general anaesthetic is required. In the case of aerophagia during NIV, it is normally diagnosed by experienced medical specialists who check on patients intermittently during NIV use. The diagnosis is based on the sound heard by listening through a stethoscope placed outside the abdominal cavity. Using this approach, the problem is sometimes detected later than when it develops, possibly also later than necessary. Belated detection of aerophagia may lead to gastric distension, which in turn, could inflate the diaphragm or cause aspiration of the stomach contents into the lungs or pneumatic rupture of the oesophagus due to extreme gastric insufflation.