Other television credits include Smallville as Kara in the season 3 finale ("Covenant"). Palicki also starred in Supernatural as Jessica Moore, Sam Winchester's doomed girlfriend, killed by a demon, in its pilot episode. The character reappears in the Supernatural season 2 episode, "What is and What Never Should Be". Palicki also appeared as Judy Robinson in John Woo's unsold pilot, The Robinsons: Lost in Space. Palicki will be starring in Legion opposite Dennis Quaid in 2009. Palicki made an appearance in the music video by Will.i.am called "We Are The Ones" in support of 2008 presidential hopeful Barack Obama.