Beginning at Redhill, near Calverton in Nottinghamshire at a roundabout with the A60, the road meets the A6097 at a junction which looks like a roundabout but actually is not, crosses the Robin Hood Way then passes Bilsthorpe. At Rufford there is a Center Parcs resort and Rufford Country Park. The road meets several roads at a major roundabout at Ollerton near a Shell petrol station. This is near Edwinstowe, famed for its connections with Robin Hood. The road passes through Clumber Park and goes past the entrance to the former Army Proteus training camp. The road passes over the River Poulter. At Apleyhead Wood, the road meets the A1 and A57 at a busy roundabout. This roundabout is due to be rebuilt to become a dual-grade junction (GSJ). The A614 overlaps the A1 for a few miles north.
At junction 34 of the A1(M) at Blyth, next to a large Moto service station, the road runs north to the settlement of Bawtry, passing to the south of a nearby colliery at Harworth. At Bawtry the road meets the A638, a Roman road which heads into Doncaster, passing under the East Coast Main Line here. At Finningley, the road passes around the runway of Robin Hood Airport Doncaster Sheffield, the former RAF Finningley. The road has a level crossing with the Doncaster-Lincoln railway line and the River Torne is crossed. Near Hatfield Woodhouse, the road passes a prison which used to be RAF Lindholme, used by RAF Bomber Command. The road meets the M180 and A18 at a roundabout at Thorne, the former terminus of the A18(M), the M18 at junction 6, follows the River Don for a few miles then crosses it where the river becomes the Dutch River.
From here, the road becomes a trunk road running through the settlements of Howden, Holme-on-Spalding-Moor, Market Weighton, Driffield, ending on the Yorkshire Coast at Bridlington, where it joins the A165.