| A428 Road | ||
| Eastbound exits | Junction | Westbound exits |
| West Midlands | ||
| Start of road | Coventry | A4600 Coventry |
| A444 Nuneaton, Burton upon Trent | Coventry | A444 Nuneaton, Burton upon Trent |
| A4082 | Coventry | A4082 |
| River Sowe | ||
| A46 Coventry Eastern Bypass | Coventry | A46 Coventry Eastern Bypass |
| Warwickshire | ||
| River Avon | ||
| A426 Leicester | Rugby | A4071 Princethorpe |
| Short (250 m) concurrency with A426 | ||
| A4071 Princethorpe | Rugby | A426 Southam |
| Oxford Canal | ||
| Northamptonshire | ||
| A5 London, Holyhead | Daventry | A5 London, Holyhead |
| A5 | Daventry | A5 |
| M1 London, Leeds | M1 J18 | M1 London, Leeds |
| Grand Union Canal | ||
| A4500 | Northampton | A4500 |
| A5080 | Northampton | A5080 |
| A5123, A508 Market Harborough | Northampton Ring Road | A5123, A508 Market Harborough |
| A508 Swan Valley | Northampton Ring Road | A508 Swan Valley |
| A5120 | Northampton Ring Road | A5120 |
| A4501 | Northampton | A4501 |
| A45 Thrapston | Nene Valley | A45 Thrapston |
| Bedfordshire | ||
| A509 Kettering, Milton Keynes | Warrington Toll Bar roundabout, Bedford | A509 Kettering, Milton Keynes |
| River Great Ouse | ||
| A422 Milton Keynes | Bedford | A422 Milton Keynes |
| A5134 Kempston | Bedford | A5134 Kempston |
| River Great Ouse | ||
| A5141 | Bedford | A5141 |
| A6 Carlisle, London | Bedford | A6 Carlisle, London |
| A5140 | Bedford | A5140 |
| A421 Buckingham | Bedford | A421 Buckingham |
| 5-mile (8 km) concurrency with A421 | ||
| A1 London, A421 Buckingham | Black Cat Roundabout | A1 London, A421 Buckingham |
| 1.5-mile (2.4 km) concurrency with A1 | ||
| A1 London, Edinburgh | Wyboston | A1 London, Edinburgh |
| Cambridgeshire | ||
| B1428 St Neots | Tithe Farm Roundabout | B1428 St Neots |
| River Great Ouse | ||
| A1198 London, Huntingdon | Caxton Gibbet roundabout | A1198 London, Huntingdon |
| local roads | Cambourne | local roads |
| Hardwick, Dry Drayton, Caldecote | Hardwick | Hardwick, Dry Drayton, Caldecote |
| A1303 Cambridge | Madingley | No exit |
| A14 Felixstowe | Girton | Start of road |
The A428 road is a major road in central and eastern England. It connects the cities of Coventry and Cambridge by way of the county towns of Northampton and Bedford.