The route starts from the A168 at Topcliffe, North Yorkshire and runs to Cowgate, Tyne and Wear where the route splits in two. The northern fork continues to Kenton Bar, where it meets the A1 and the A696, while the southern fork heads west, again terminating at the A1, this time at Westerhope.
From the Topcliffe A168 Junction, the route runs north through Northallerton, and crosses the A66 road just east of the A66(M) section. It runs on through Darlington, across A1(M) junction 59, and on to Newton Aycliffe, Ferryhill, Durham and Chester-le-Street.
The A167 bypass at Chilton near Ferryhill was completed and opened to traffic on 20 June 2005. Construction had started in 2004, 65 years after first proposed when the route was still the A1.
Beyond Chester-le-Street the A167 continues to A1(M) junction 63 and through Birtley before crossing the A1 at the junction near the Angel of the North. (The first route of the Great North Road ran via Wrekenton on the present B1296. The second route ran via Low Fell on the A167. The third route ran from the A1(M) junction 65 via the A194(M) and the A19 Tyne Tunnel, to the Wideopen A1/A19 Junction.)
The start point of the Great North Run is on the A167(M) Central Motorway in Newcastle.
Originally the road was the A1(M), but changes to the route of the A1 have caused changes to the route number. When the A1 was re-routed through the Tyne Tunnel, it was renumbered as the A6127(M) - becoming one of only two four-digit, Axxxx(M) motorways. After the construction of the A1 western bypass, the Tyne Tunnel became the A19 and the A6127(M) became the A167(M).
The A167(M) is unusual in that it has a slip road leading from an unclassified road directly onto the right-hand ("fast") lane at Camden Street; a result of its two-tier construction. It also has other junctions where entry to and exit from the motorway is via the outside lane, which can lead to a lot of weaving and conflicting traffic movement. The A167(M) is subject to a 50mph speed limit throughout.
| A167(M) Motorway | ||
| Northbound exits | no junction numbers | Southbound exits |
| Road continues as A167 to Kenton, Gosforth and Jesmond, South Gosforth, Newcastle city centre B1318 | Start of Motorway | |
| North Shields, Tynemouth A1058 | North Shields, Tynemouth A1058 | |
| Byker A193, B1307 | (Manors) | Byker A193, B1307 |
| Start of Motorway | (Swan House) | Road continues as A167 to Gateshead, South Shields and Newcastle city centre, Byker, Elswick A186 |