The death of Masterton raised an issue about the use of helmets in hockey - whether they should be mandatory, and whether they affect a player's abilities. Response was mixed in the helmet debate even in the days following Masterton's death: Gordie Howe claimed that he would not, but nevertheless encouraged the next generation of players to do so, while Bobby Hull claimed that he was in serious consideration. At one extreme, Stafford Smythe claimed that helmets should be made mandatory.
As for the game itself, only two players would wear helmets: J. C. Tremblay, who had worn a helmet all season, and Brian Conacher, as a result of Masterton's death.
On the day of the all-star game, the National Hockey League Writers' Association proposed that a trophy should be presented in Masterton's honor, and by the end of the season, the league made it a reality. The Bill Masterton Memorial Trophy is awarded to each year to the player who best exemplifies dedication, perseverance, and sportsmanship.
As it turned out, this year would be the last in which the defending champions faced off against a team consisting of the "best of the rest" - NHL president Clarence Campbell hinted that the following year would be the first in which there would be an East-versus-West battle, citing that the game could be easily moved to different cities. The 21st classic would also be the last in which the teams were determined based on the previous season's First and Second All-Star Teams, a move supported by the absence of then-rookie Bobby Orr in the last year's game and the fact that the game had moved to mid-season.
As an aside, despite the somber mood, Toronto coach Punch Imlach celebrated their silver wedding anniversary the night of the All-Star Game.
| Toronto | 9 | 18 | 14 | 41 |
| All-Stars | 19 | 11 | 10 | 40 |