January 3
| Medium on BBC. |
| January 4
| Committed on NBC. |
| January 6
| Wickedly Perfect on CBS |
| January 8
| Ned's Declassified School Survival Guide on Nickelodeon |
| January 9
| Zoey 101 on Nickelodeon |
| January 13
| Tilt on ESPN |
| January 21
| American Dragon: Jake Long on Disney Channel |
| January 14
| Battlestar Galactica on SciFi |
| January 23
| NUMB3RS on CBS |
| February 14
| Kudlow & Company on CNBC |
| February 16
| The Apprentice on BBC Two |
| February 19
| Mew Mew Power (Tokyo Mew Mew in Japan and the manga version) debuts on 4Kids TV |
| February 21
| Avatar: The Last Airbender on Nickelodeon |
| March 7
| Fat Actress premieres on Showtime |
| March 11
| Wonder Showzen premieres on MTV2 |
| March 14
| Mad Money on CNBC |
| March 18
| The Suite Life of Zack and Cody on Disney Channel |
| March 24
| The Office (US version) premieres on NBC) |
| March 26
| Doctor Who Confidential, accompanying the revived Doctor Who, begins on BBC Three |
| March 27
| Grey's Anatomy on ABC |
| April 1
| The Eyes of Nye |
| April 12
| Deadliest Catch on Discovery Channel |
| May 1
| American Dad! on FOX |
| May
| Kept, Game Show Moments Gone Bananas, BSTV, and Strip Search on VH1 |
| May 28
| Attack of the Show! on G4 |
| May 30
| The Life and Times of Juniper Lee on Cartoon Network |
| June
| Weeds on Showtime |
| June 2
| Beauty and the Geek premieres on The WB |
| June 20
| Wildfire premieres on ABC Family |
| July 6
| Mind of Mencia premieres on Comedy Central |
| July 7
| Big Brother 6 on CBS |
| July 8
| Camp Lazlo on Cartoon Network |
| July 9
| Catscratch on BBC. |
| July 20
| So You Think You Can Dance premieres on FOX |
| August 8
| Roobarb and Custard Too on Five |
| August 13
| Magical DoReMi on 4Kids TV |
| August 29
| Prison Break on FOX |
| September 10
| G.I. Joe Sigma 6 starts airing on 4Kids TV |
| September 10
| Naruto, (a popular anime series from Japan), makes its North American debut on Cartoon Network's Toonami block. |
| September 13
| Supernatural on the WB |
| September 13
| Bones on FOX |
| September 17
| Johnny Test, Loonatics Unleashed and Coconut Fred's Fruit Salad Island on Kids' WB! |
| September 18
| Life With Derek on Family Channel |
| September 19
| How I Met Your Mother on CBS |
| September 19
| Surface on NBC |
| September 20
| Tittybangbang on BBC Three |
| September 20
| My Name Is Earl on NBC |
| September 21
| Britain's Next Top Model on Living |
| September 22
| Criminal Minds on CBS |
| September 22
| Everybody Hates Chris on UPN |
| September 23
| Ghost Whisperer on CBS |
| September 24
| Afterlife on ITV1 in the UK. However, despite being a British series, it had actually had its world premiere some weeks earlier on Australia's ABC network. |
| September 27
| Commander in Chief on ABC |
| October 10
| Yu-Gi-Oh! GX, a spin-off to Yu-Gi-Oh! Duel Monsters, debuts on Cartoon Network |
| October 17
| The Colbert Report, a spin-off from The Daily Show, debuts on Comedy Central. |
| October 18
| Da Vinci's City Hall, a sequel to Da Vinci's Inquest, premieres on CBC |
| October 27
| Bleak House (UK), a 15-episode adaptation of the Charles Dickens novel of the same name designed to capture a soap opera-style audience by using Dickens's original serial structure in half-hour episodes, debuts on BBC One. |
| October 30
| House of Harmony, also known as Das Haus Der Harmonie (German), debuted on Germany's ZDF channel to a primetime viewership of over seven million viewers. It starred Singaporean actress Fann Wong (of Shanghai Knights fame) and Germany-based English actor Philippe Brenninkmeyer |
| October 31
| The UK version of Deal or No Deal on Channel 4, relaunching the career of Noel Edmonds and bringing the channel a surprise daytime hit. |
| November 5
| IGPX, the first Toonami original series, debuts on Cartoon Network (US). |
| November 6
| The Boondocks, based on the popular yet controversial American comic strip, debuts on Cartoon Network (US). |
| November 25
| The X's on Nickelodeon |
| December 19
| The U.S. version of Deal or No Deal debuts on NBC as a week-long event. It returned for another week on February 27, 2006 before running a weekly shift that currently runs 3 nights a week. |
| Date
| Name
| Age
| Cinematic Credibility |
| January 2
| Cyril Fletcher
| 91
| British comedian (That's Life!) |
| January 23
| Johnny Carson
| 79
| American comedian, host of The Tonight Show for 30 years. |
| March 10
| Dave Allen
| 68
| Irish comedian, host of solo shows on BBC1 and ITV. |
| March 25
| Paul Henning
| 93
| producer (The Beverly Hillbillies, Petticoat Junction, Green Acres) |
| April 5
| Debralee Scott
| 52
| actress, game show panelist (Mary Hartman, Mary Hartman, Match Game) |
| April 26
| Mason Adams
| 86
| actor (Lou Grant) |
| May 22
| Thurl Ravenscroft
| 91
| actor, TV's Tony the Tiger of Kellogg's Frosted Flakes commercials. |
| May 26
| Eddie Albert
| 99
| actor (Green Acres) |
| June 24
| Paul Winchell
| 82
| actor (The Smurfs, Wacky Races, The New Adventures of Winnie the Pooh) |
| June 25
| John Fiedler
| 80
| actor (The Bob Newhart Show, Buffalo Bill, The New Adventures of Winnie the Pooh) |
| June 26
| Richard Whiteley
| 61
| presenter, host of Countdown. |
| July 11
| Gretchen Franklin
| 94
| actress. |
| July 20
| James Doohan
| 85
| actor (Scotty on the original Star Trek) |
| August 7
| Peter Jennings
| 67
| ABC news anchor |
| August 8
| Barbara Bel Geddes
| 82
| actress (Eleanor "Miss Ellie" Southworth Ewing Farlow on Dallas), of lung cancer |
| August 9
| Kay Tremblay
| 91
| actress (Road to Avonlea) |
| August 23
| Brock Peters
| 78
| actor. |
| September 2
| Bob Denver
| 70
| actor (Gilligan's Island, The Many Loves of Dobie Gillis) |
| September 25
| Don Adams
| 82
| actor (Get Smart, Tennessee Tuxedo, and Inspector Gadget) |
| October 2
| Nipsey Russell
| 87
| actor/comedian. |
| October 3
| Ronnie Barker
| 76
| comedian, half of The Two Ronnies |
| October 5
| Ray Bumatai
| 53
| actor |
| October 7
| Charles Rocket
| 56
| actor (Saturday Night Live) |
| October 31
| Mary Wimbush
| 81
| actress (Poldark, Jeeves and Wooster, Century Falls) |
| November 13
| Eddie Guerrero
| 38
| professional wrestler and star of WWE Smackdown |
| November 24
| Pat Morita
| 72
| Japanese-American actor |
| November 29
| Wendie Jo Sperber
| 47
| actress (Babes, Bosom Buddies) |
| December 16
| John Spencer
| 58
| actor (The West Wing, L.A. Law) |