The 6th Presidents Cup Matches were held in 2005 between September 20 and September 25. They were played at the Robert Trent Jones Golf Club in Gainesville, Virginia, USA. The United States team won the competition by a margin of 18½–15½. The honorary chairmen was former President of the United States George H. W. Bush.
| International | Results | United States |
|---|---|---|
| Scott/Goosen | 4 and 3 | Woods/Couples |
| Singh/Hensby | halved | Funk/Furyk |
| O'Hern/Clark | 1 up | Mickelson/DiMarco |
| Lonard/Appleby | 4 and 2 | Leonard/Verplank |
| Campbell/Cabrera | 2 and 1 | Love/Perry |
| Immelman/Weir | 6 and 5 | Cink/Toms |
| 3½ | Foursomes | 2½ |
| 3½ | Overall | 2½ |
| International | Results | United States |
|---|---|---|
| Campbell/Cabrera | halved | Mickelson/DiMarco |
| Scott/Goosen | 3 and 1 | Couples/Toms |
| Immelman/Weir | 2 and 1 | Leonard/Verplank |
| Singh and Tim Clark | halved | Funk/Cink |
| Lonard/Nick O'Hern | 3 and 2 | Love/Perry |
| Appleby/Hensby | 3 and 2 | Woods/Furyk |
| 3 | Four-Ball | 3 |
| 6½ | Overall | 5½ |
| International | Results | United States |
|---|---|---|
| Goosen/Scott | halved | Leonard/Verplank |
| Campbell/Cabrera | 5 and 3 | Mickelson/DiMarco |
| Singh/Appleby | halved | Woods/Furyk |
| Clark/O'Hern | 2 and 1 | Funk/Toms |
| Immelman/Weir | 1 up | Love/Cink |
| 2 | Foursomes | 3 |
| 8½ | Overall | 8½ |
| International | Results | United States |
|---|---|---|
| Goosen/Scott | 5 and 4 | Leonard/Verplank |
| Lonard/O'Hern | 6 and 5 | Mickelson/DiMarco |
| Campbell/Cabrera | halved | Love/Couples |
| Hensby/Clark | 5 and 3 | Perry/Cink |
| Singh/Appleby | 2 up | Woods/Furyk |
| 2½ | Four-Ball | 2½ |
| 11 | Overall | 11 |
| International | Results | United States |
|---|---|---|
| Clark | 4 and 3 | Leonard |
| Immelman | 2 and 1 | Toms |
| Goosen | 2 and 1 | Woods |
| Hensby | 4 and 3 | Perry |
| Singh | 1 up | Couples |
| Weir | 3 and 2 | Verplank |
| Scott | 3 and 2 | Furyk |
| Lonard | 3 and 2 | Cink |
| Campbell | 3 and 2 | Funk |
| O'Hern | 4 and 3 | Love |
| Cabrera | halved | Mickelson |
| Appleby | 1 up | DiMarco |
| 4½ | Singles | 7½ |
| 15½ | Overall | 18½ |
| 2003 Presidents Cup Tied at 17 | 2005 Presidents Cup USA 18½ International 15½ | 2007 Presidents Cup USA 19½ International 14½ |