When a Hurricane Katrina victim hallucinates on a plane, an old friend of House, Dylan Crandall (D. B. Sweeney), takes on the role of the victim's parent, but House doesn't believe that he is really the father.
House runs the paternity test from the beginning, but lies about running it. After House successfully diagnoses the patient, he then admits running the test, but lies about the results. Crandall is not her father, but House tells the girl that he is. He also doesn't challenge his old friend's conviction.
Cuddy asks House for help selecting a sperm donor, but House lambastes choosing a father out of a genetic lineup. She should pick someone she knows and trusts, which Cuddy takes to mean himself. To which House dismisses by saying "Someone you like."