tuberculosis (TB)

formerly consumption

Bacterial disease caused by some species of mycobacterium (tubercle bacillus). Mentioned in ancient Egyptian records and by Hippocrates, it has occurred throughout history worldwide. In the 18th–19th centuries it reached near-epidemic proportions in the rapidly industrializing and urbanizing Western world, where it was the leading cause of death until the early 20th century. TB resurged in the 1980s, spreading from AIDS patients to others, especially in prisons, homeless shelters, and hospitals, since enclosed settings promote spread. It occurs worldwide and is still a major cause of death in many countries. The body isolates the bacilli by forming tiny tubercles (nodules) around them. This often arrests TB's progress and no symptoms occur, but if the disease is not treated, it may become active—and contagious—later in life, most often when the immunity of the infected individual is suppressed (e.g., AIDS, after organ transplant). The original tubercle breaks down, releasing still viable bacilli into the bloodstream to cause a new infection, which starts with loss of energy and weight and persistent cough. Health deteriorates, with increasing cough and possibly pleurisy (see thoracic cavity) and spitting up blood. Growing tubercle masses may destroy so much lung tissue that respiration cannot supply the body with enough oxygen. Other organs can be affected, with complications including meningitis. A vaccine with weakened bacteria has helped control infection, but preventing exposure by recognizing and treating active TB early is more effective. Because many strains are resistant to drugs, treatment requires at least two drugs to which the patient's strain is sensitive and at least six months; inadequate treatment lets resistant bacilli multiply. The acute disease caused by multidrug-resistant strains is very hard to cure and usually fatal.

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The White Plague (1982) is a science fiction novel by Frank Herbert.

Plot

When a bomb planted by the IRA goes off, the wife and children of molecular biologist John Roe O'Neill are killed on May 20, 1996. Driven insane by loss, he plans a genocidal revenge and creates a plague that kills women. O'Neill then releases it in Ireland (for supporting the terrorists), England (for oppressing the Irish and giving them a cause), and Libya (for training said terrorists); he demands that the governments of the world send all citizens of those countries back to their countries, and that they quarantine those countries and let the plague run its course, so they will lose what he has lost; if they don't, he has more plagues to release.

Further details

O'Neill is driven halfway insane by the death of his family, and his mind fragments into several personalities that carry out his plan for him. After releasing the plague, he goes to Ireland to hide, planning to offer his services as a molecular biologist in the hopes of sabotaging whatever work is done there on finding a cure. When he arrives in Ireland, he is suspected of being O'Neill (whom the investigatory agencies of the world have deduced is responsible). To travel to the lab at Killaloe, he is forced to walk with a priest, a boy struck mute by the death of his mother, and Joseph Herity, the IRA bomber who detonated the explosive that killed O'Neill's wife and children; their purpose is to confirm his identity, either through Herity's indirect questioning, or the possibility that he will confess to the priest when confronted with the pain his revenge has caused for the boy.

Meanwhile, law and order have broken down in England and Ireland, and the old Irish ways are coming back. Local IRA thugs appoint themselves 'kings of old', and others recreate old, pagan religions centered on the rowan tree. The IRA has effective control of Ireland, but as the governments of the world grow certain that O'Neill is there and essentially in custody, they consider wiping out the three targeted countries to end the lingering threat.

Major themes

Typical of a Herbert novel, most of the drama is mental, political, and communal. While the story of O'Neill and his revenge is told in full, there is also the larger story of how the governments of the world's countries deal with the plague, which escapes into limited areas that are quickly sterilized by "panic fire", which immolates everything and everyone in it. North Africa is wiped out; Boston is burned to the ground; Rome is destroyed with atomic bombs; and the U.S. pushes for a moat of cobalt dust to isolate Africa, which is written off as a total loss.

The world's armed forces are reorganized under a Canadian Admiral, Francois Delacourt, who heads Barrier Command, responsible for the absolute separation of contaminated and clean areas. Scientists toy with a conspiracy of intellectuals to override the expected repression of research by governments. In countries around the world, angry mobs lynch Irish, English, and Libyans, and anyone too closely resembling them.

Awards

The White Plague was nominated for a Locus Award for best science fiction novel in 1983 but lost to Isaac Asimov’s novel Foundation's Edge.