Whewellite, or at least crystalline calcium oxalate, does also arise from natural sources. Small crystals or flakes are sometimes found on the surfaces of some cacti, and kidney stones frequently have the same composition.
Whewellite was named after William Whewell (1794-1866), an English mineralogist.
Whewellite is used as a thermogravimetric analysis standard due to its well known decomposition temperatures and products.