, an infarction
is the process resulting in a macroscopic
area of necrotic
tissue in some organ caused by loss of adequate blood supply
. Supplying arteries
may be blocked from within by some obstruction (e.g. a blood clot
or fatty cholesterol
deposit), or may be mechanically compressed or ruptured by trauma.
Infarction is commonly associated with atherosclerosis, where an atherosclerotic plaque ruptures, a thrombus forms on the surface occluding the blood flow and occasionally forming an embolus that occludes other blood vessels downstream. Infarction can also involve mechanical blockage of the blood supply, such as when part of the gut herniates or twists.
Infarctions are divided into two types according the amount of hemorrhaging
Diseases commonly associated with infarctions include: