During his reign Sennacherib encountered various problems with Babylonia. His first campaign took place in 703 BC against Marduk-apla-iddina II who had seized the throne of Babylon and gathered an alliance supported by Chaldeans, Aramaeans, and Elam. We can date the visit of Babylonian ambassadors to Hezekiah of Judah in this period. The allies wanted to make use of the unrest that arose at the accession of Sennacherib. Sennacherib split his army and had one part attack the stationed enemy at Kish while he and the rest of the army proceeded to capture the city Cutha. After that was done the king returned swiftly to aid the rest of his army. The rebellion was defeated and Marduk-apla-iddina II fled. Babylon was taken, and its palace plundered but its citizens were left unharmed. The Assyrians searched for Marduk-apla-iddina II, especially in the southern marshes, but he was not found. The rebellion forces in the Babylonian cities were wiped out and a Babylonian named Bel-Ibni who was raised at the Assyrian court was placed on the throne. When the Assyrians left, Marduk-apla-iddina II started to prepare another rebellion. In 700 BC the Assyrian army returned to fight the rebels in the marshes again. Not surprisingly, Marduk-apla-iddina II fled again to Elam and died there.
Bel-Ibni proved to be unloyal to Assyria and was taken back a prisoner. Sennacherib tried to solve the problem of the Babylonian rebellion by placing someone loyal to him on the throne, namely his son Ashur-nadin-shumi. It didn’t help. Another campaign was led six years later, in 694 BC, to destroy the Elamite base on the shore of the Persian Gulf. To accomplish this, Sennacherib had obtained Phoenician and Syrian boats which sailed with the rest of his army down the Tigris to the sea. The Phoenicians were not used to the tide of the Persian Gulf which caused a delay. The Assyrians battled the Chaldeans at the river Ulaya and won the day. While the Assyrians were busy at the Persian Gulf, the Elamites invaded northern Babylonia in a complete surprise. Sennacherib's son was captured and taken to Elam and his throne was taken over by Nergal-Ushezib. The Assyrians fought their way back north and captured various cities, in the meanwhile a year had passed as it was now 693 BC.
A large battle was fought against the Babylonian rebels at Nippur, their king was captured and in turn taken to Nineveh. For the loss of his son Sennacherib launched another campaign into Elam where his army started to plunder cities. The Elamite king fled to the mountains and Sennacherib was forced to return home because of the coming winter. Another rebellion leader, named Mushezib-Marduk claimed the Babylonian throne and was supported by Elam. The last great battle was fought in 691 BC with an uncertain result which enabled Mushezib-Marduk to remain on the throne for another two years. This was only a brief respite because shortly afterwards Babylon was besieged which led to its fall in 689 BC. Sennacherib claimed to have destroyed the city and indeed the city was unoccupied for several years.haha
Sennacherib first recounts several of his previous victories, and how his enemies had become overwhelmed by his presence. He was able to do this to Great Sidon, Little Sidon, Bit-Zitti, Zaribtu, Mahalliba, Ushu, Akzib and Akko. After taking each of these cities, Sennacherib installed a puppet leader named Ethbaal as ruler over the entire region. Sennacherib then turned his attention to Beth-Dagon, Joppa, Banai-Barqa, and Azjuru, cities that were ruled by Sidqia and also fell to Sennacherib.
Egypt and Nubia then came to the aid of the stricken cities. Sennacherib defeated the Egyptians and, by his own account, single-handedly captured the Egyptian and Nubian charioteers. Sennacherib captured and sacked several other cities, including Lachish (the second most-strongly fortified city in the Kingdom of Judah). He punished the "criminal" citizens of the cities, and he reinstalled Padi, their leader, who had been held as a hostage in Jerusalem.
After this, Sennacherib turned to King Hezekiah of Judah, who stubbornly refused to submit to him. Forty-six of Hezekiah's cities (cities 1st millennium BCE terms ranged in size from large modern-day towns to villages) were conquered by Sennacherib, but Jerusalem did not fall. His own account of this invasion, as given in the Taylor prism, is as follows:
Because Hezekiah, king of Judah, would not submit to my yoke, I came up against him, and by force of arms and by the might of my power I took 46 of his strong fenced cities; and of the smaller towns which were scattered about, I took and plundered a countless number. From these places I took and carried off 200,156 persons, old and young, male and female, together with horses and mules, asses and camels, oxen and sheep, a countless multitude; and Hezekiah himself I shut up in Jerusalem, his capital city, like a bird in a cage, building towers round the city to hem him in, and raising banks of earth against the gates, so as to prevent escape... Then upon Hezekiah there fell the fear of the power of my arms, and he sent out to me the chiefs and the elders of Jerusalem with 30 talents of gold and 800 talents of silver, and diverse treasures, a rich and immense booty... All these things were brought to me at Nineveh, the seat of my government.
when Sanacharib, king of the Arabians and Assyrians, marched his vast army into Egypt, the warriors one and all refused to come to his (i.e., the Pharaoh Sethos) aid. On this the monarch, greatly distressed, entered into the inner sanctuary, and, before the image of the god, bewailed the fate which impended over him. As he wept he fell asleep, and dreamed that the god came and stood at his side, bidding him be of good cheer, and go boldly forth to meet the Arabian host, which would do him no hurt, as he himself would send those who should help him. Sethos, then, relying on the dream, collected such of the Egyptians as were willing to follow him, who were none of them warriors, but traders, artisans, and market people; and with these marched to Pelusium, which commands the entrance into Egypt, and there pitched his camp. As the two armies lay here opposite one another, there came in the night, a multitude of field-mice, which devoured all the quivers and bowstrings of the enemy, and ate the thongs by which they managed their shields. Next morning they commenced their fight, and great multitudes fell, as they had no arms with which to defend themselves. There stands to this day in the temple of Vulcan, a stone statue of Sethos, with a mouse in his hand, and an inscription to this effect - "Look on me, and learn to reverence the gods."
Sennacherib is sometimes credited with the invention of the Archimedes screw for the purpose of irrigation, although evidence for this is contentious.