A vaso-occlusive crisis
or sickle cell crisis is a common painful complication of sickle cell anemia
in adolescents and adults. It occurs when the circulation of blood vessels
is obstructed by sickled red blood cells
, causing ischemic
injuries. The most common complaint is of pain, and recurrent episodes may cause irreversible organ damage.
Related symptoms are dactylitis, priapism, abdominal pain, and jaundice.