Twisted vein distended with blood. Varix also covers arteries and lymphatic vessels (see lymphatic system). Varicose veins occur mostly in the legs, when malfunctioning valves let blood pool in veins near the skin. Causes include hereditary valve and vein wall weakness and internal or external pressure on veins. Varices are common in pregnancy, suggesting that hormone abnormalities play a role. Symptoms include a heavy feeling, with leg cramps and swelling after standing a long time. Complications include skin ulcers and thrombosis. Treatment involves strong support hose, injection therapy, or surgery. Varices in the esophagus, which often occur in liver disease, can ulcerate and bleed. Seealso hemorrhoid.
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After passing anterior to the medial malleolus (where it often can be visualized and palpated), it runs up the medial side of the leg.
At the knee, it runs over the posterior border of the medial epicondyle of the femur bone.
The great saphenous vein then courses laterally to lie on the anterior surface of the thigh before entering an opening in the fascia lata called the saphenous opening.
It joins with the femoral vein in the region of the femoral triangle.
Near the fossa ovalis it is joined by the superficial epigastric, superficial iliac circumflex, and superficial external pudendal veins.
A vein, named the thoracoepigastric, runs along the lateral aspect of the trunk between the superficial epigastric vein below and the lateral thoracic vein above and establishes an important communication between the femoral and axillary veins.
The great saphenous vein is the conduit of choice for vascular surgeons, when available, for doing peripheral arterial bypass operations because it has superior long-term patency compared to synthetic grafts (PTFE, PETE (Dacron)), human umbilical vein grafts or biosynthetic grafts [Omniflow]. Often, it is used in situ (in place), after tying off smaller tributaries and stripping the valves with a device called LeMaitre's valvulotome.
The saphenous nerve is a branch of the femoral nerve that runs with the great saphenous vein and is often damaged in surgeries that make use of the similarly named vein.