In her writings, Druyan has stressed the idea that people can have a sense of awe and wonder about the unity of the cosmos without introducing the concept of a god. Before she met Sagan, "Her interest in science came primarily from her interest in the philosophy of Karl Marx. . . . Druyan herself had, at the time, rather vaporous standards of evidence for her many sundry beliefs (as she later acknowledged). She believed . . . that Immanuel Velikovsky in the 1950s had correctly deduced the truth about the solar system. . . . She believed in the ancient astronauts of Erich von Daniken.
In the areas of film and television, she was one of the writers for the television series Cosmos, and a producer of the film Contact. Most recently, she is the CEO and a co-founder of Cosmos Studios. In 2007 she was said to be working on an IMAX film on global warming as well as a sequel to Cosmos.
She has served on the Board of Directors of the National Organization for the Reform of Marijuana Laws NORML for over 10 years, and is also the current president of the NORML Foundation Board of Directors.
Other projects that she has been involved in include the selection of the music on the Voyager Golden Record mounted on the Voyager 1 and Voyager 2 space probes, and the Cosmos 1 spacecraft, which intended to demonstrate solar sail propulsion. The Cosmos 1 used a former Soviet submarine missile as a launch vehicle (in keeping with the "swords into plowshares" philosophy) but due to a malfunction in separation, the Cosmos 1 never reached stable orbit.
She attended and was a speaker at the Beyond Belief symposium in November 2006.