is the name of:
- Pieter-Dirk Uys (born 1945), South African satirist, anti-apartheid activist and gay liberation activist
- Antoinette Uys (born 1976), South African badminton player
- Jamie Uys (1921-1996), South African film director (born as Jacobus Johannes Uys)
- Stanley Uys liberal editor and political commentator
- Uys Krige (christened Mattheus Uys Krige) (1910-1987), South African writer, poet, playwright, translator, rugby player, war correspondent and romantic
- The surname of a prominent South African family.