Medically, first used in 1912. Introduced in anaesthesia in 1942. The correct chemical structure was only elucidated circa 1970, even though the plant had been known since the Spanish Conquest.
The word curare comes from the South American Indian name for the arrow poison: "ourare". Presumably the initial syllable was pronounced with a heavy glottal stroke. Tubocurarine is so called because the plant samples containing it were first shipped to Europe in tubes.
Today, tubocurarine has fallen into disuse in western medicine, as safer synthetic alternatives such as atracurium are available. However, tubocurarine is still used in the United States and elsewhere as part of the lethal injection procedure.
HSDB 2152. Isoquinoline Alkaloid. Tubadil. Mecostrin. Intracostin. Intocostrin.
Transient use of tricaine to remove the telencephalon has no residual effects on physiological recordings of supramedullary/ dorsal neurons of the cunner, Tautogolabrus adspersus.
Oct 01, 2003; When used as a general anesthetic, tricaine significantly alters physiological parameters recorded from supramedullary/dorsal...