Tryptophan alpha,beta-oxidase

L-tryptophan + O₂ $rightleftharpoons$ alpha,beta-didehydrotryptophan + H₂O₂

Thus, the two substrates of this enzyme are L-tryptophan and O₂, whereas its two products are alpha,beta-didehydrotryptophan and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is L-tryptophan:oxygen alpha,beta-oxidoreductase. Other names in common use include L-tryptophan 2',3'-oxidase, and L-tryptophan alpha,beta-dehydrogenase. It employs one cofactor, heme.

References

• Genet R, Denoyelle C, Menez A "Purification and partial characterization of an amino acid alpha,beta- dehydrogenase, L-tryptophan 2',3'-oxidase from Chromobacterium violaceum". J. Biol. Chem. 269 18177–84.
• Genet R, Benetti PH, Hammadi A, Menez A "L-tryptophan 2',3'-oxidase from Chromobacterium violaceum. Substrate specificity and mechanistic implications". J. Biol. Chem. 270 23540–5.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes