In enzymology, a triacylglycerol---sterol O-acyltransferase is an enzyme that catalyzes the chemical reaction

triacylglycerol + a 3beta-hydroxysterol rightleftharpoons diacylglycerol + a 3beta-hydroxysterol ester

Thus, the two substrates of this enzyme are triacylglycerol and 3beta-hydroxysterol, whereas its two products are diacylglycerol and 3beta-hydroxysterol ester.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is triacylglycerol:3beta-hydroxysterol O-acyltransferase. This enzyme is also called triacylglycerol:sterol acyltransferase.


  • Zimowski J and Wojciechowski ZA "Acyl donors for sterol esterification by cell-free preparations from Sinapis alba roots". Phytochemistry 20 1799–1803.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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