Sign of the times may refer to:

• Sign of the Times, a compilation album by progressive metal band, Queensrÿche
• Signs of the Times (for North America), a monthly magazine published by Pacific Press, also available in Spanish as El Centinela
• Signs of the Times (news website), an alternative news website
• Signs of the Times (Australia) , a monthly magazine published by Signs Publishing Company
• Signs of the Times (UK), a British left-wing discussion group
• Sign “☮” the Times, a 1987 song, album and film by Prince
• Sign of the times (Catholicism), a phrase associated with some reformist members of the Roman Catholic Church
• "A Sign of the Times", a 1966 single by Petula Clark
• "Sign of the Times", a 1983 single by British all-female group The Belle Stars.