Inducible T-cell co-stimulator (CD278 or ICOS) has proven to be a particularly critical signal for ThF cells, although it is not clear if that role is in induction or progressive maturation. Also Bcl-6 is a factor identified in ThF cells, but it may have roles that extend beyond this subset, because it has been implicated in memory CD8+ T cell development.
Finally, it has been shown that dysregulated ThF cells can cause systemic autoimmunity and auto-antibody production or contribute to T cell–mediated organ-specific autoimmunity.
BASF plans THF and PolyTHF investment in China. (Business & Finance News: Asia/ Pacific).(tetrahydrofuran)(Brief Article)
May 01, 2002; BASF says it plans to build an integrated plant to produce tetrahydrofuran (thf) and polythf at Caojing, China. The...