The quiz consists of 841 questions in several categories, named after various faculties of the University, such as Thaumatology, Arcane History, Dwarf Studies, and Oook. Each section contains a bonus question, and several ways exist to score more points for a question, many of them ludicrous.
David Langford has intentionally not based his questions on the Annotated Pratchett File, a long list of Discworld trivia available on the internet. Nevertheless several items are in both the APF and the quizbook.
This book divides the questions into guilds. For example, if it is a question about a joke it may be categorised as in the Fools' Guild.