Definitions

sutherland jr., earl

Earl Wilbur Sutherland, Jr.

[suhth-er-luhnd]
Earl Wilbur Sutherland Jr. (November 19, 1915March 9, 1974) was an American pharmacologist and biochemist. Sutherland was born in Burlingame, Kansas. He won a Nobel Prize in Physiology or Medicine in 1971 "for his discoveries concerning the mechanisms of the action of hormones," especially epinephrine, via second messengers (such as cyclic adenosine monophosphate, cyclic AMP).

He received his bachelor's degree in chemistry in 1937 from Washburn University, Topeka, Kansas and earned his medical degree in 1942 from Washington University School of Medicine in St. Louis. After serving as a doctor in World War II, he returned to Washington University as a researcher in the pharmacology laboratory of Nobel laureate Carl Ferdinand Cori. In 1953, he became director of the department of pharmacology at Case Western Reserve University (then Western Reserve University) in Cleveland, Ohio, where he discovered the role of cyclic AMP in mediating the action of certain hormones. In 1963, desiring to limit his duties to research, Sutherland moved to Vanderbilt University School of Medicine in Nashville where he was a professor of physiology until 1973. Vanderbilt is also home to a residential dormitory, Sutherland House, named in Sutherland's Honor. A plaque and photographic display commemorate his achievements. He was elected to the National Academy of Sciences in 1966, won the Albert Lasker Award for basic medical research in 1970, and received the National Medal of Science in 1973. At the time of his death in 1974, Sutherland was a distinguished professor of biochemistry at University of Miami Medical School.

References

  • Shampo, M A; Kyle R A (2000). "Earl Sutherland--Nobel Prize for Hormone Research". Mayo Clin. Proc. 75 (6): 552.
  • Raju, T N (1999). "The Nobel chronicles. 1971: Earl Wilbur Sutherland, Jr. (1915-74)". Lancet 354 (9182): 961.
  • Butcher, R W; Robison G A (1975). "An appreciation of Earl Sutherland". Metab. Clin. Exp. 24 (3): 237-40.
  • Ho, R J; Russell T, Asakawa T (1975). "The last conversation with Dr. Earl W. Sutherland, Jr: the feedback regulation of cyclic nucleotides". Metab. Clin. Exp. 24 (3): 257-64.
  • (1974). "Dr. Sutherland, AHA career investigator, dies in Miami". Circ. Res. 34 (5): 743.
  • Oye, I (1971). "[The Nobel Prize in Medicine to Earl W. Sutherland Jr]". Tidsskr. Nor. Laegeforen. 91 (31): 2270-1.
  • (1971). "[Nobel prize for Medicine and Physiology 1972]". Münchener medizinische Wochenschrift (1950) 113 (45): Suppl 45:1.
  • Kampmeier, R H (1971). "Cycl AMP--and the Nobel Prize". South. Med. J. 64 (11): 1413-4.
  • (1971). "[Nobel prize for medicine 1971]". Dtsch. Med. Wochenschr. 96 (44): 1735.
  • (1971). "Nobel prize". Br Med J 4 (5781): 188.
  • (1971). "1971 Nobel Prize for physiology and medicine". Triangle; the Sandoz journal of medical science 10 (4): 173-4.
  • Ishikawa, E (1969). "[Profile of Professor Earl W. Sutherland Jr]". Nippon Rinsho 27 (4): 1301-4.

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