He later became suspicious of the PI crew when he realized that they were discarding pieces of concrete across the prison yard, from the hole they had been digging in the Break Room. After the PI head, John Abruzzi was briefly replaced by Gus Fiorello, C-Note bribed him to work in PI. He discovered the hole that Michael and crew had dug as part of the escape plan. When Abruzzi regained control of PI, C-Note threatened the crew to let him on board or he would tell the guards.
C-Note later became a respected member of the team when he helped the team out of several problems that nearly derailed the escape plan. He also befriended Charles Westmoreland as they both shared the same need to see their family again. One consequence of his joining the escape team, however, was C-Note being ostracized by other black inmates, ironically for the same reason C-Note had initially refused to deal with Michael: consorting with T-Bag, who had also joined the escape team. C-Note had two violent encounters with his former associates and only the escape prevented him from being killed.
After the "Fox River Eight's" escape, C-Note, Michael, Lincoln, Sucre and Abruzzi met bigger problems as their escape plane took off and left them stranded with numerous police on their trail.
The next morning, C-Note, Michael, Lincoln, Sucre and Abruzzi continue to run from the authorities, narrowly running past a freight train to evade their pursuers. C-Note becomes the outspoken man of the fugitive group. He chastises Scofield for failing to openly disclose to the group the existence of Westmoreland's money in Tooele, Utah and he also demanded that Abruzzi be abandoned because he took a young girl hostage when her father recognized the five as the Fox River escapes. C-Note is focused on rejoining his family and the little trust he ever had for his fugitive comrades appears to be wearing thin. His wife and daughter were, up until the start of second season, unaware of his incarceration as he had managed to trick them into thinking he is still serving overseas in Iraq. They learned the truth when his escape made the news.
By episode 3 "Scan", C-Note contacted his wife by pay phone and she was quite upset with his lies and even doubted that he was ever in the US Military. C-Note promised to explain everything and that he would come into a lot of money soon. He said in 7 days, that they would meet at the "Rainbow Room" at the window where they had their picture. Eavesdropping FBI agents assumed they meant a city restaurant. C-Note later meets his daughter at school and asks her to tell her mother to turn the porch light on at 7 o'clock as an indication of her trust. By the episode's end, C-Note is skulking about near his family's home, while an FBI Agent Lang interviews his wife.
C-Note then proceeds to make his own play for Westmoreland's money by taking a train to Utah. Borrowing a laptop and notepad from the commuter sitting next to him, C-Note accesses an online military database run by the United States Army Signal Corps to find the site where the money is buried. Unfortunately, midway through Preston, Idaho, an attendant tells him that his ticket is not valid. C-Note attempts to reason with him, but the attendant calls for security. Out of options, C-Note is forced to bolt out a window, into a nearby river. He passes through Cache County, Utah and inquires about an RV for sale. He is told that it will cost $40,000. C-Note replies that he will be back in a couple of days with cash.
He is later seen hitchhiking when Sucre, driving past on his motorcycle, agrees to give him a ride. They arrive in Tooele and are reunited with Michael. They proceed to dig for the money. Unfortunately, a house had been built over the burial site. Though the fugitives were initially able to fool the residents into thinking they were maintenance men, they eventually got wise. C-Note loudly voiced his disapproval to Michael about taking innocent people hostage, and his old tensions with T-Bag also resurfaced. But these feelings later give way to excitement when they finally dig up the money. Unfortunately for C-Note, Sucre chooses this moment to double cross them all and demands the money from them while holding them at gun point. C-Note immediately leaves for his family after seeing that the money is gone. In the episode "Unearthed", he meets up with his old friends back in Chicago for help with executing his plan to reunite his family. He and his wife, Kacee, and daughter Dede finally have their reunion in an alley after a narrow escape from the federal agents.
In the episode "Disconnect", C-Note has a happy time with his family until his daughter complains of stomach problems. Kacee tells him that they don't have her medication, and they leave to find a pharmacy. While buying medication, the pharmacist recognizes Kacee, and on the pretence of needing change from the back room, calls the authorities. Kacee is arrested, but not before she drops the medication into the trash so C-Note could pick it up from there.
C-Note and his daughter return in "John Doe". C-Note is guilt-ridden over his wife's arrest, and tries to see if Kacee will be allowed bail. He plans for her to skip bail and rejoin him, and for the family to move to Alaska. However, Kacee's bail is denied.
In the episode "Chicago" C-Note and Dede are in a Benson, Minnesota diner when Dede becomes sick due to her lack of medication. C-Note prepares to leave when suddenly, a man holds up the diner with a gun. After C-Note stops the man from holding up the diner, a female customer the robber was planning to kill lets him leave despite knowing his wanted status. Despite this, Agent Mahone receives a report that C-Note was spotted at the diner, and that his daughter was sick. Mahone arrives in Minnesota, but C-Note manages to evade him by boarding a train. After C-Note nearly resorts to painful means at a free clinic to help his daughter, he calls Mahone and offers to turn himself in so that Dede will receive proper treatment, asking also that his wife be released. Mahone agrees, and in return, C-Note must give him information on Michael -- the website Europeangoldfinch.net, which C-Note overheard Michael telling Sucre about in Utah. When C-Note could not find Michael's location, Mahone forces C-Note to hang himself, under orders from Agent Kim, in exchange for his wife and daughter's well-being. The episode ends just as C-Note jumps off his cell bed with the noose around his neck, but he is saved by a guard in the next episode. In the prison infirmary, he phones the FBI and demands to speak to Mahone, but Agent Wheeler (Jason Davis), who happens to be investigating Mahone, answers the call instead. Wheeler says he can keep C-Note safe if he tells him what Mahone asked him to do.
A week later, Wheeler has C-Note released from prison and placed in the Witness Protection Program with his family in exchange for testifying against Mahone. This would be C-Note's last appearance. To date, C-Note is the only member of the Fox River Eight to successfully evade capture by the authorities. It is unknown if he will return to the show.