There are five difficulty levels from which to choose. In the easiest level, kids can mix and match the characters' heads, torsos and feet any way they like. In higher levels of play, there are more puzzle pieces, some of which are upside down, and characters must be assembled in their original left-to-right order. Puzzles range in size from 9 to 25 pieces. The fifth level has a time limit which, when beaten, will give the player bonus points.
The manual for Dr. Seuss' Fix-Up the Mix-Up Puzzler claims that the game promotes problem-solving strategies, logic, pattern recognition, memory and a variety of other early learning skills.