Despite these earlier creations the title of Earl of Guilford is chiefly associated with one branch of the North family. This branch of the family descends from the prominent lawyer and politician the Hon. Sir Francis North, second son of Dudley North, 4th Baron North (see the Baron North for earlier history of the family). He was Chief Justice of the Common Pleas from 1675 to 1682 and Lord Keeper of the Great Seal from 1682 to 1685. In 1683 he was created Baron Guilford, of Guilford in the County of Surrey, in the Peerage of England. He died at an early age and was succeeded by his son, the second Baron. He served as President of the Board of Trade from 1713 to 1714 and was also Lord-Lieutenant of Essex. His son, the third Baron, represented Banbury in the House of Commons. In 1734 he succeeded his cousin as seventh Baron North and in 1752 he was honoured when he was created Earl of Guilford in the Peerage of Great Britain.
He was succeeded by his son, the second Earl. Known mainly under his courtesy title of Lord North, which he used from 1752 to 1790, he was one of the most influential statesman of the second half of the 18th century. As Prime Minister of Great Britain between 1770 and 1782, he was a major figure in the American Revolution. North also held two of the other great offices of state, those of Chancellor of the Exchequer and Home Secretary. He was succeeded by his eldest son, the third Earl. He represented several constituencies in the House of Commons. Lord Guilford had no sons and on his death the barony of North fell into abeyance between his daughters (see the Baron North for further history of this title). He was succeeded in the barony of Guilford and the earldom by his younger brother, the fourth Earl. He died childless and was succeeded by his younger brother, the fifth Earl. He was Member of Parliament for Banbury from 1792 to 1794 and also served as Governor of Ceylon from 1798 to 1805.
He was also childless and on his death the titles passed to his cousin, the sixth Earl. He was a clergyman. He was succeeded by his grandson, the seventh Earl. His son, the eighth Earl, was a Lieutenant-Colonel in the Royal East Kent Yeomanry. When he died the peerages were inherited by his grandson, the ninth Earl. As of 2007 the titles are held by the latter's only son, the tenth Earl, who succeeded in 1999. Three other members of the North family may also be mentioned. Frederic Dudley North (1866-1921), great-grandson of Reverend Charles Augustus North, younger brother of the sixth earl, was a prominent civil servant in Australia. His son Charles Frederic North (1887-1979) was Speaker of the Legislative Assembly of Western Australia from 1947 to 1953. Jonathan North (b. 1931), son of the Hon. John Montagu William North, second son of the eighth Earl, succeeded his maternal grandfather as second Baronet, of Southwell, in 1947 (see North Baronets).
Lacking a different secondary title, the heirs apparent to the earldom have continued to use, without any legal basis, Lord North as a courtesy title. An unqualified reference to Lord North almost always refers to Frederick North, Lord North, later second Earl of Guilford.
The Heir Apparent is the present holder's son Frederick North, Lord North (b. 2002)