In some cases where there are legal, religious or social restrictions on two people having physical intimacy, there may even be such restrictions on just being together in a secluded place. For example, under traditional schools of sharia or Islamic law, a man and a woman who are not married and not mahram, being together in a house, a room, a bathroom, or a secluded place may be forbidden. See also yichud.

Seclusion may be used as a control tactic in psychiatric treatment settings. Seclusion of an agitated person in a quiet room free of stimulation may help de-escalate a situation which may be dangerous to the agitated person or those around him.

Seclusion of a single person is also called solitude.