Pesticides can also be classed as synthetic pesticides or biological pesticides (biopesticides), although the distinction can sometimes blur.
Broad-spectrum pesticides are those that kill an array of species, while narrow-spectrum, or selective pesticides only kill a small group of species.
A systemic pesticide moves inside a plant following absorption by the plant. With insecticides and most fungicides, this movement is usually upward (through the xylem) and outward. Increased efficiency may be a result. Systemic insecticides which poison pollen and nectar in the flowers may kill needed pollinators such as bees.
Most pesticides work by poisoning pests.
Pesticides can save farmers money by preventing crop losses to insects and other pests; in the US, farmers get an estimated four-fold return on money they spend on pesticides. One study found that not using pesticides reduced crop yields by about 10%. Another study,conducted in 1999, found that a ban on pesticides in the United States may result in a rise of food prices, loss of jobs, and an increase in world hunger.
DDT, sprayed on the walls of houses, is an organochloride that has been used to fight malaria since the 1950s. Recent policy statements by the World Health Organization have given stronger support to this approach. Dr. Arata Kochi, WHO's malaria chief, said, "One of the best tools we have against malaria is indoor residual house spraying. Of the dozen insecticides WHO has approved as safe for house spraying, the most effective is DDT." However, since then, an October 2007 study has linked breast cancer from exposure to DDT prior to puberty. Scientists estimate that DDT and other chemicals in the organophosphate class of pesticides have saved 7 million human lives since 1945 by preventing the transmission of diseases such as malaria, bubonic plague, sleeping sickness, and typhus. However, DDT use is not always effective, as resistance to DDT was identified in Africa as early as 1955, and by 1972 nineteen species of mosquito worldwide were resistant to DDT. A study for the World Health Organization in 2000 from Vietnam established that non-DDT malaria controls were significantly more effective than DDT use. The ecological effect of DDT on organisms is an example of bioaccumulation.
In the 1940s manufacturers began to produce large amounts of synthetic pesticides and their use became widespread. Some sources consider the 1940s and 1950s to have been the start of the "pesticide era." Pesticide use has increased 50-fold since 1950 and 2.3 million tonnes (2.5 million imperial tons) of industrial pesticides are now used each year. Seventy-five percent of all pesticides in the world are used in developed countries, but use in developing countries is increasing.
In the 1960s, it was discovered that DDT was preventing many fish-eating birds from reproducing, which was a serious threat to biodiversity. Rachel Carson wrote the best-selling book Silent Spring about biological magnification. The agricultural use of DDT is now banned under the Stockholm Convention on Persistent Organic Pollutants, but it is still used in some developing nations to prevent malaria and other tropical diseases by spraying on interior walls to kill or repel mosquitoes.
In most countries, in order to sell or use a pesticide, it must be approved by a government agency. For example, in the United States, the Environmental Protection Agency (EPA) does so. Complex and costly studies must be conducted to indicate whether the material is safe to use and effective against the intended pest. During the registration process, a label is created which contains directions for the proper use of the material. Based on acute toxicity, pesticides are assigned to a Toxicity Class.
Some pesticides are considered too hazardous for sale to the general public and are designated restricted use pesticides. Only certified applicators, who have passed an exam, may purchase or supervise the application of restricted use pesticides. Records of sales and use are required to be maintained and may be audited by government agencies charged with the enforcement of pesticide regulations.
In Canada, over 140 municipalities and the entire province of Quebec have now placed restrictions on the cosmetic use of synthetic lawn pesticides as a result of health and environmental concerns. The Ontario provincial government promised on September 24, 2007 to also implement a province-wide ban on the cosmetic use of lawn pesticides, for protecting the public. Medical and environmental groups support such a ban. On April 22, 2008, the Provincial Government of Ontario announced that it will pass legislation that will prohibit, province-wide, the cosmetic use and sale of lawn and garden pesticides. The Ontario legislation would also echo Massachusetts law requiring pesticide manufacturers to reduce the toxins they use in production. The Province of Prince Edward Island is also considering such legislation. On April 3, 2008, the Canadian Cancer Society released opinion poll results conducted by Ipsos Reid, which established that a clear majority of residents in the provinces of British Columbia and Saskatchewan want province-wide cosmetic lawn pesticide bans, and that the majority of respondents believe that cosmetic pesticides are a threat to their health.
Though pesticide regulations differ from country to country, pesticides and products on which they were used are traded across international borders. To deal with inconsistencies in regulations among countries, delegates to a conference of the United Nations Food and Agriculture Organization adopted an International Code of Conduct on the Distribution and Use of Pesticides in 1985 to create voluntary standards of pesticide regulation for different countries. The Code was updated in 1998 and 2002. The FAO claims that the code has raised awareness about pesticide hazards and decreased the number of countries without restrictions on pesticide use.
Two other efforts to improve regulation of international pesticide trade are the United Nations London Guidelines for the Exchange of Information on Chemicals in International Trade and the United Nations Codex Alimentarius Commission. The former seeks to implement procedures for ensuring that prior informed consent exists between countries buying and selling pesticides, while the latter seeks to create uniform standards for maximum levels of pesticide residues among participating countries. Both initiatives operate on a voluntary basis.
Reading and following label directions is required by law in countries such as the US and in limited parts of the rest of the world.
One study found pesticide self-poisoning the method of choice in one third of suicides worldwide, and recommended, among other things, more restrictions on the types of pesticides that are most harmful to humans.
The American Medical Association recommends limiting exposure to pesticides and using safer alternatives:
Particular uncertainty exists regarding the long-term effects of low-dose pesticide exposures. Current surveillance systems are inadequate to characterize potential exposure problems related either to pesticide usage or pesticide-related illnesses…Considering these data gaps, it is prudent…to limit pesticide exposures…and to use the least toxic chemical pesticide or non-chemical alternative.
The World Health Organisation and the UN Environment Programme estimate that each year, 3 million workers in agriculture in the developing world experience severe poisoning from pesticides, about 18,000 of whom die. According to one study, as many as 25 million workers in developing countries may suffer mild pesticide poisoning yearly.
Organophosphate pesticides have increased in use, because they are less damaging to the environment and they are less persistent than organochlorine pesticides. These are associated with acute health problems for workers that handle the chemicals, such as abdominal pain, dizziness, headaches, nausea, vomiting, as well as skin and eye problems. Additionally, many studies have indicated that pesticide exposure is associated with long-term health problems such as respiratory problems, memory disorders, dermatologic conditions, cancer, depression, neurological deficits, miscarriages, and birth defects. Summaries of peer-reviewed research have examined the link between pesticide exposure and neurologic outcomes and cancer, perhaps the two most significant things resulting in organophosphate-exposed workers.
According to researchers from the National Institutes of Health (NIH), licensed pesticide applicators who used chlorinated pesticides on more than 100 days in their lifetime were at greater risk of diabetes. In a paper appearing in the May, 2008, issue of the American Journal of Epidemiology, researchers said the associations between specific pesticides and incident diabetes ranged from a 20 percent to a 200 percent increase in risk. New cases of diabetes were reported by 3.4 percent of those in the lowest pesticide use category compared with 4.6 percent of those in the highest category. Risks were greater when users of specific pesticides were compared with applicators who never applied that chemical.
In the EU, MRLs are set by DG-SANCO In the US, levels of residues that remain on foods are limited to tolerance levels that are established by the US EPA and are considered safe. The EPA sets the tolerances based on the toxicity of the pesticide and its breakdown products, the amount and frequency of pesticide application, and how much of the pesticide (i.e., the residue) remains in or on food by the time it is marketed and prepared. Tolerance levels are obtained using scientific risk assessments that pesticide manufacturers are required to produce by conducting toxicological studies, exposure modeling and residue studies before a particular pesticide can be registered, however, the effects are tested for single pesticides, and there is little information on possible synergistic effects of exposure to multiple pesticide traces in the air, food and water.
A study published by the United States National Research Council in 1993 determined that for infants and children, the major source of exposure to pesticides is through diet. A study in 2006 measured the levels of organophosphorus pesticide exposure in 23 school children before and after replacing their diet with organic food (food grown without synthetic pesticides). In this study it was found that levels of organophosphorus pesticide exposure dropped dramatically and immediately when the children switched to an organic diet.
To reduce the amounts of pesticide residues in food, consumers can wash, peel, and cook their food; trim the fat from meat; and eat a variety of foods to avoid repeat exposure to a pesticide typically used on a given crop. Consumers can also buy food that is grown organically, though even organic food may have traces of pesticides.
Strawberries and tomatoes are the two crops with the most intensive use of soil fumigants. They are particularly vulnerable to several type of diseases, insects, mites, and parasitic worms. In 2003, in California alone, 3.7 million pounds of metam sodium were used on tomatoes. In recent years other farmers have demonstrated that it is possible to produce strawberries and tomatoes without the use of harmful chemicals and in a cost effective way.
The Bhopal disaster occurred when a pesticide plant released 40 tons of methyl isocyanate (MIC) gas, a chemical intermediate in the synthesis of some carbamate pesticides. The disaster immediately killed nearly 3,000 people and ultimately caused at least 15,000 deaths.
In China, an estimated half million people are poisoned by pesticides each year, 500 of whom die.
Children have been found to be especially susceptible to the harmful effects of pesticides. A number of research studies have found higher instances of brain cancer, leukemia and birth defects in children with early exposure to pesticides, according to the Natural Resources Defense Council. Often used for ridding school buildings of rodents, insects, pests, etc., pesticides only work temporarily and must be re-applied. The poisons found in pesticides are not selectively harmful to just pests and in everyday school environments children (and faculty) are exposed to high levels of pesticides and cleaning materials. "No testing has ever been done specifically pertaining to threats among children
Peer-reviewed studies now suggest neurotoxic effects on developing animals from organophosphate pesticides at legally-tolerable levels, including fewer nerve cells, lower birth weights, and lower cognitive scores. The EPA finished a 10 year review of the organophosphate pesticides following the 1996 Food Quality Protection Act, but did little to account for developmental neurotoxic effects, drawing strong criticism from within the agency and from outside researchers.
Some scientists think that exposure to pesticides in the uterus may have negative effects on a fetus that may manifest as problems such as growth and behavioral disorders or reduced resistance to pesticide toxicity later in life.
A new study conducted by the Harvard School of Public Health in Boston, has discovered a 70% increase in the risk of developing Parkinson's disease for people exposed to even low levels of pesticides.
A 2008 study from Duke University found that the Parkinson's patients were 61 percent more likely to report direct pesticide application than were healthy relatives. Both insecticides and herbicides significantly increased the risk of Parkinson's disease.
One study found that use of pesticides may be behind the finding that the rate of birth defects such as missing or very small eyes is twice as high in rural areas as in urban areas. Another study found no connection between eye abnormalities and pesticides.
Pyrethrins, insecticides commonly used in common bug killers, can cause a potentially deadly condition if breathed in.
Pesticides can be created that are targeted to a specific pest's life cycle, which can be more environmentally-friendly. For example, potato cyst nematodes emerge from their protective cysts in response to a chemical excreted by potatoes; they feed on the potatoes and damage the crop. A similar chemical can be applied to fields early, before the potatoes are planted, causing the nematodes to emerge early and starve in the absence of potatoes.
Cultivation practices include polyculture (growing multiple types of plants), crop rotation, planting crops in areas where the pests that damage them do not live, timing planting according to when pests will be least problematic, and use of trap crops that attract pests away from the real crop. In the US, farmers have had success controlling insects by spraying with hot water at a cost that is about the same as pesticide spraying.
Release of other organisms that fight the pest is another example of an alternative to pesticide use. These organisms can include natural predators or parasites of the pests. Biological pesticides based on entomopathogenic fungi, bacteria and viruses cause disease in the pest species can also be used.
Interfering with insects' reproduction can be accomplished by sterilizing males of the target species and releasing them, so that they mate with females but do not produce offspring. This technique was first used on the screwworm fly in 1958 and has since been used with the medfly, the tsetse fly, and the gypsy moth. However, this can be a costly, time consuming approach that only works on some types of insects.
In India, traditional pest control methods include using Panchakavya, the "mixture of five products." The method has recently experienced a resurgence in popularity due in part to use by the organic farming community.
Some evidence shows that alternatives to pesticides can be equally effective as the use of chemicals. For example, Sweden has halved its use of pesticides with hardly any reduction in crops. In Indonesia, farmers have reduced pesticide use on rice fields by 65% and experienced a 15% crop increase.