Rufino is a city in the province of Santa Fe, Argentina. It has 18,372 inhabitants as per the . It lies on the southwest of the province, from the provincial capital Santa Fe, near the borders with Córdoba (west) and Buenos Aires (south), on the intersection of National Routes 33 and 7.

The town was founded by Gerónimo Segundo Rufino in 1886, as the railway line that linked Diego de Alvear, Santa Fe, to Villa Mercedes, San Luis, was inaugurated. The plans for the new town were approved by the governorship of Santa Fe on 29 March 1889, which is acknowledged as the official foundation date.

References

• Municipality of Rufino — Official website.