Definitions
retinol&o=10616

Phosphatidylcholine-retinol O-acyltransferase

In enzymology, a phosphatidylcholine---retinol O-acyltransferase is an enzyme that catalyzes the chemical reaction

phosphatidylcholine + retinol---[cellular-retinol-binding-protein] rightleftharpoons 2-acylglycerophosphocholine + retinyl-ester---[cellular-retinol-binding-protein]

Thus, the two substrates of this enzyme are phosphatidylcholine and retinol---[cellular-retinol-binding-protein], whereas its two products are 2-acylglycerophosphocholine and retinyl-ester---[cellular-retinol-binding-protein].

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is phosphatidylcholine:retinol---[cellular-retinol-binding-protein] O-acyltransferase. Other names in common use include lecithin---retinol acyltransferase, phosphatidylcholine:retinol-(cellular-retinol-binding-protein), and O-acyltransferase.

References

  • MacDonald PN, Ong DE "Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine". J. Biol. Chem. 263 12478–82.
  • Saari JC, Bredberg DL "Lecithin:retinol acyltransferase in retinal pigment epithelial microsomes". J. Biol. Chem. 264 8636–40.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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