He was involved in September 1720 in the wrangle by the Viceroy to destitute the Captain General of the Province of Caracas, Marcos de Bethencourt y Castro, and appointing him as a Governor and Lieutenant of the Captain General, which required a further Order from February 1721 and obeying it by the local authorities as from May 1721. By September, he was replaced and then moved to La Habana (Cuba) and Veracruz (Mexico), towards the end of 1722, coming back to Spain towards the end of 1723. In 1726 he publishes statements in the sense that the vacant positions in the churches of the Spanish Empire, and therefore the rents and moneys providing their support for whathever earlier reasons, belong to the King ("regalism" from the French churches, hence the marquis title given to him "de la Regalía" by the thankful Bourbon King Philip V of Spain, bringing "over 1 million "reales"" to the Crown).
Meanwhile his administrative position within the Exchequer rolled on : Casa de Contratación de Cadiz, Finances Council, the Royal Monopolies on Salt, Mines, Mercury, African Slaves, Tobacco, Foreign Trade, China-Mexico trade from Manila (Philippine Islands), Foreign residents and Merchants..... , getting promoted to Marquis in 1738 by King Philip V, heavily mentally handicapped by then, but assisted by loyal commoners and industriously minded nobility.
It is said, that notified the "Cabildo Council" of the Canary Islands on his promotion to the Castile nobility there was never a reply or official congratulation about his title.
His son, known as Felix José de Abreu Bertodano, (Caracas, 13 July 1721 - circa 1765, aged 45) was also a brilliant merchantilist and writer on economic subjects.