receptor protein

CAMP receptor protein

cAMP receptor protein (in short CRP, also known as catabolite gene activator protein (in short CAP)) is a regulatory protein in bacteria. This protein binds cAMP, which causes a conformational change that allows the protein to bind tightly to a specific DNA sequence in the promoters of the genes it controls. The genes regulated by this protein are mostly involved in energy metabolism, such as galactose, citrate, or the PEP group translocation system.


External links

crystal structure of CRP and binding site properties

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