The Excelsior was the pathfinder, or prototype of its class, as all other ships of the same design are called Excelsior-class ships. Many Excelsior-class ships have been featured in various episodes of the Star Trek spinoff series, Star Trek: The Next Generation and Star Trek: Deep Space Nine. The USS Enterprise-B, the third Federation Starfleet vessel to bear the name Enterprise, was an Excelsior-class ship, as established in the 1994 feature film Star Trek Generations.
By the time she was seen much more extensively in Star Trek VI, the ship had been reclassified as NCC-2000. Several fan-based Star Trek technical guides give details on the reasons for the failure of the transwarp drive. However, there is no canonical reference to the fate of the transwarp program, but given that even 24th century vessels still lacked transwarp, it can be logically assumed that the experiment was a failure. This is mentioned in notes in The Star Trek Encyclopedia, which is written by Star Trek staff.
The Excelsior-class spaceframe proved to be remarkably durable, able to withstand considerable punishment both from the elements and enemy vessels alike (in Star Trek VI, Excelsior sustains a direct photon torpedo strike to the saucer section, only to have it absorbed by the shields). This accounts for the considerable number of vessels remaining in Starfleet, even several decades later into the era of Star Trek: The Next Generation and Star Trek: Deep Space Nine. Notable appearances of Excelsior class are shown in DS9 episodes "Paradise Lost" and "For the Uniform". Several Excelsior class ships were also used in battles with The Dominion
A USS Excelsior is mentioned in the TNG episode Interface, which searched for the USS Hera, commanded by the mother of Enterprise-D chief engineer Geordi La Forge. It is unknown if it is the same vessel as seen in the TOS-era films, and her class is not mentioned.
Two different bridge sets were seen for Excelsior. The first set is seen in Star Trek III: The Search For Spock when she departed spacedock in pursuit of the USS Enterprise, which had just been stolen by Captain Kirk. In this film, only the parts of the bridge that would be seen on screen were actually constructed. For Star Trek VI: The Undiscovered Country a new and complete bridge set was built (actually a re-dress of the Enterprise-A bridge). This bridge had a large status panel directly behind the Captain's chair. It also had helm and navigation consoles similar in appearance to the conn and ops consoles on the bridge of a Galaxy-class starship.
In the video game Star Trek: Shattered Universe, the USS Excelsior travels to the mirror universe and back, under the command of Captain Sulu.