The 3 substrates of this enzyme are (2R)-3-sulfolactic acid, NAD+, and NADP+, whereas its 4 products are 3-sulfopyruvic acid, NADH, NADPH, and H+. This enzyme is important in the metabolism of archaea, particularly their biosynthesis of coenzymes such as coenzyme M, tetrahydromethanopterin and methanofuran.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-2-hydroxyacid:NAD(P)+ oxidoreductase. Other names in common use include (R)-sulfolactate:NAD(P)+ oxidoreductase, L-sulfolactate dehydrogenase, ComC, and (R)-sulfolactate dehydrogenase.
BIOMERIEUX, INC. ISSUES URGENT EXPANDED PRODUCT RECALL FOR VITEK[R] 2 PIPERACILLIN/ TAZOBACTAM TEST ON GRAM NEGATIVE SUSCEPTIBILITY CARDS.
Apr 08, 2011; WASHINGTON -- The following information was released by the U.S. Food and Drug Administration (FDA): As a follow up to the...