, a homocysteine desulfhydrase
is an enzyme
the chemical reaction
- L-homocysteine + H2O hydrogen sulfide + NH3 + 2-oxobutanoate
Thus, the two substrates of this enzyme are L-homocysteine and H2O, whereas its 3 products are hydrogen sulfide, NH3, and 2-oxobutanoate.
This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-homocysteine hydrogen-sulfide-lyase (deaminating 2-oxobutanoate-forming). Other names in common use include homocysteine desulfurase, L-homocysteine hydrogen-sulfide-lyase, and (deaminating). This enzyme participates in nitrogen metabolism and sulfur metabolism. It employs one cofactor, pyridoxal phosphate.
- KALLIO RE "Function of pyridoxal phosphate in desulfhydrase systems of Proteus morganii". J. Biol. Chem. 192 371–7.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes