(myelin-proteolipid) O-palmitoyltransferase

In enzymology, a [myelin-proteolipid] O-palmitoyltransferase is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + [myelin proteolipid] rightleftharpoons CoA + O-palmitoyl-[myelin proteolipid]

Thus, the two substrates of this enzyme are palmitoyl-CoA and myelin proteolipid, whereas its two products are CoA and O-palmitoyl-myelin proteolipid.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase. Other names in common use include myelin PLP acyltransferase, acyl-protein synthetase, and myelin-proteolipid O-palmitoyltransferase.


  • Bizzozero OA, McGarry JF, Lees MB "Acylation of endogenous myelin proteolipid protein with different acyl-CoAs". J. Biol. Chem. 262 2138–45.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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