is a hypothesised protein
, most likely a cysteine protease enzyme
that occurs only in fetal
cells. Its activity appears to be the activation of factor X
, one of the coagulation factors
, and would account for the increased incidence of thrombosis
in cancer patients. Tissue factor
(TF) is also known to be present at increased levels around malignant cells.
- De Cicco M. The prothrombotic state in cancer: pathogenic mechanisms. Crit Rev Oncol Hematol 2004;50:187-96. PMID 15182825.