Jones was born in Floyd County, Georgia. He became a missionary Baptist preacher in Jackson, Mississippi, where he met Mason in 1895. In 1896, Jones, Mason, and two other radical preachers held a faith healing revival in Jackson. The doctrine of sanctification that was presented at this revival was not approved of by Jones' church. In 1897, he and Mason were both thrown out of their church for their beliefs in the holiness movement and abstinence. They started their own church, first preaching in supporters' homes and eventually in a former gin house.
Jones is the author of over 1000 hymns. Some of his known hymns which are still sung around the world are Deeper, Deeper, I Will Make the Darkness Light, Come Unto Me, Where Shall I Be, I'm Happy With Jesus Alone and Jesus Only. He pastored churches in Arkansas, Mississippi, and California.
In 1907, he split with Charles Harrison Mason over the doctrine of speaking in tongues as an evidence of the Holy Spirit. In 1909, the Christian Women Willing Workers (CWWW), now the United Christian Women’s Ministries (UCWM) was established upon the recommendation of Sis. Maria Williams. Jones made his first trip to Los Angeles in 1915 to conduct a revival for Bishop William A. Washington and helped him organize and incorporate the Bethel Church of Christ (Holiness) U.S.A. Also, in 1915, Elder Charles Mason, who became Bishop Charles Mason, incorporated the Church of God in Christ which he founded. The mission was misunderstood. What we don’t understand we fear and fight. Conflicts caused the holiness movement to separate into many denominations. It was first called the movement, then Church of God, Church of Christ, Church of God in Christ, Church of Christ (Holiness) U.S.A.
In 1916, Bishop Jones wife Fannie Brown died in Little Rock, Arkansas. He moved to Los Angeles in 1917 and organized Christ Temple Church of Christ (Holiness) U.S.A. in an upstairs hall at Washington and Central. Jones married Pearl E. Reed on January 4, 1918 to this union three sons were born, Charles Price Jones Jr., Vance Reed Jones and Samuel Sherman Jones. In 1921, the first property bought for Christ Temple was on 37th and Naomi. Then in 1926, a church and parsonage was purchased for $18,000 on the corner of 54th and Hooper. In 1922 the church created a council of Bishops in the national convocation and he was chosen to be the first Senior Bishop. He actively maintained the spiritual leadership and operated as Senior Bishop of the church until he fell ill in 1943 and underwent major surgery. Because of his declining health, he attended his last convention in 1944 in Chicago, Illinois where he was elected Senior Bishop and President Emeritus of the National Convention for life. Jones departed this life and went home to be with the Lord in Los Angeles, California on January 19, 1949. His homegoing service was held at Christ Temple Church (54th and Hooper) on January 25, 1949 at 1:00pm. He is buried with his wife Pearl who later died on August 13, 1972 at Evergreen Cemetery in Los Angeles. He was succeeded by Bishop Major Rudd Conic who in 1967 relocated Christ Temple Church to its current location on 54th and 10th Ave.